The burden of resistant tuberculosis is on the rise which is a threat to WHO END Tuberculosis programme .
Children are also becoming victim but data are not sufficient yet
Primary resistance:When an individual is infected with resistant strain of Mycobacterium tuberculosis
Secondary resistance:When an individual is infected with drug sensitive strain of Mycobacterium tuberculosis but during the course of treatment the organism acquire resistance due to suboptimal treatment,incomplete treatment with high bacterial load.It is also known as acquired resistance.
MONORESISTANCE:When the organism is resistant to only one drug
POLYRESISTANCE;When the organism is resistant to 2 drugs but not to both Rifampicin and Isoniazid
MULTI DRUG RESISTANCE(MDR): When there is resistance to both Rifampicin and Isoniazid
PRE EXTENSIVELY RESISTANCE(PRE-XDR):When there is resistance to Rifampicin,Isoniazid with resistance to either Fluoroquinolones or Second line injectables(SLI) but not to both.
EXTENSIVELY DRUG RESISTANCE:When there is resistance to Rfampicin ,Isoniazid and both Fluoroquinolones and SLI
RR Tb: When there is resistance to Rifampicin with or without resistance to other anti tuberculosis drug
SLI(second line injectables): Amikacin,Kanamycin and Capreomycin
REFERENCES:Indian Journal of Pediatrics,volume 87/number 10/October 2020